TFE Female Formula provides synergistic nutrients along with ovarian and uterine tissue extracts specifically formulated for the support and regulation of the female reproductive organs. Deficiencies in progesterone and estrogen, hormones secreted by the ovaries, have been linked to premenstrual syndrome, perimenopause and menopause. Stress, environmental contaminants, excessive alcohol and antibiotic use, along with a diet high in sugar, carbohydrates and fats can contribute to disturbances of the reproductive system.